Wikipedia says:
"Countless pubs, restaurants, cafés, galleries and little shops create a day and nightlife atmosphere unrivalled in the rest of Berlin. Along with Schöneberg and Mitte, Prenzlauer Berg is a focal point of the Berlin art scene. Along with Friedrichshain and Kreuzberg it is also a popular neighbourhood with the student population.

Prenzlauer Berg is one of the most popular districts in Berlin, is one of Berlin's prettiest neighbourhoods, still central, yet quieter than Berlin Mitte." Read more here.